T Sano Selected Research

1-methyl-1,2,3,4-tetrahydroisoquinoline

11/2001	Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
9/2001	Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.

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T Sano Research Topics

Disease

29	Neoplasms (Cancer) 12/2017 - 01/2000
22	Stomach Neoplasms (Stomach Cancer) 10/2020 - 11/2000
11	Carcinoma (Carcinomatosis) 04/2016 - 01/2000
9	Shock 02/2022 - 05/2000
9	Neoplasm Metastasis (Metastasis) 01/2010 - 03/2001
6	Adenocarcinoma 02/2017 - 09/2009
5	Lymphatic Metastasis 09/2009 - 01/2000
4	Thrombosis (Thrombus) 01/2017 - 11/2000
4	Klatskin Tumor 05/2013 - 03/2001
4	Pituitary Neoplasms (Pituitary Adenoma) 12/2001 - 03/2000
3	Inflammation (Inflammations) 03/2017 - 01/2003
3	Colorectal Neoplasms (Colorectal Cancer) 03/2010 - 07/2001
3	Adenoma (Adenomas) 12/2001 - 03/2000
3	Hepatocellular Carcinoma (Hepatoma) 10/2001 - 06/2001
3	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 08/2001 - 02/2000
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2001 - 02/2001
2	Insulin Resistance 01/2021 - 03/2017
2	Obesity 01/2021 - 03/2017
2	Pancreatic Fistula (Pancreatic Fistulas) 01/2018 - 09/2005
2	Infections 06/2017 - 08/2001
2	Fibrosis (Cirrhosis) 04/2015 - 01/2014
2	Necrosis 01/2015 - 11/2007
2	Lung Neoplasms (Lung Cancer) 01/2010 - 07/2008
2	Hemorrhage 02/2005 - 11/2001
2	Atherosclerosis 01/2005 - 11/2000
2	Parkinsonian Disorders (Parkinsonism) 11/2001 - 01/2001
2	Myocardial Infarction 10/2001 - 03/2001
2	Hypokinesia (Bradykinesia) 09/2001 - 07/2001
2	Parkinson Disease (Parkinson's Disease) 09/2001 - 07/2001
2	Leukopenia 07/2001 - 05/2001
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Pleural Effusion (Pleural Effusions) 01/2019
1	Myasthenia Gravis 01/2019
1	Myocarditis (Carditis) 01/2019
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Communicable Diseases (Infectious Diseases) 01/2018
1	Margins of Excision 12/2017
1	Coronary Disease (Coronary Heart Disease) 03/2017
1	Body Weight (Weight, Body) 02/2017
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 02/2017
1	Diarrhea 02/2017
1	Mucositis 02/2017

Drug/Important Bio-Agent (IBA)

5	Messenger RNA (mRNA)IBA 05/2013 - 03/2000
3	Protons (Proton)IBA 05/2012 - 09/2000
3	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2001 - 08/2001
3	Proteins (Proteins, Gene)FDA Link 10/2001 - 09/2000
2	Indicators and Reagents (Reagents)IBA 10/2020 - 03/2006
2	Biomarkers (Surrogate Marker)IBA 01/2015 - 06/2007
2	Protein Isoforms (Isoforms)IBA 01/2014 - 01/2003
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 07/2010 - 08/2001
2	Dacarbazine (DIC)FDA LinkGeneric 02/2005 - 12/2001
2	CytokinesIBA 01/2004 - 01/2003
2	suplatast tosilateIBA 01/2004 - 01/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2004 - 01/2003
2	Immunoglobulin E (IgE)IBA 01/2003 - 10/2001
2	S100 Proteins (S 100 Protein)IBA 03/2002 - 10/2000
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2001 - 07/2001
2	1-methyl-1,2,3,4-tetrahydroisoquinolineIBA 11/2001 - 09/2001
2	1,2,3,4-tetrahydroisoquinolineIBA 11/2001 - 09/2001
2	Phosphotransferases (Kinase)IBA 10/2001 - 07/2001
2	monteplaseIBA 10/2001 - 03/2001
2	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2001 - 03/2001
2	RNA (Ribonucleic Acid)IBA 08/2001 - 03/2000
2	Carboplatin (JM8)FDA LinkGeneric 07/2001 - 05/2001
2	Docetaxel (Taxotere)FDA Link 07/2001 - 05/2001
2	Tumor Suppressor Protein p14ARF (p14ARF)IBA 03/2001 - 09/2000
1	ursodoxicoltaurineIBA 01/2021
1	Amyloid (Amyloid Fibrils)IBA 01/2021
1	Ethanol (Ethyl Alcohol)IBA 07/2019
1	AmmoniaIBA 07/2019
1	Cholinergic ReceptorsIBA 01/2019
1	AntibodiesIBA 01/2019
1	Vancomycin FDA LinkGeneric 01/2018
1	Transcription Factors (Transcription Factor)IBA 06/2017
1	Catechin (Z 7300)IBA 03/2017
1	Prealbumin (Transthyretin)IBA 02/2017
1	Fluorouracil (Carac)FDA LinkGeneric 02/2017
1	Famotidine (Pepcid)FDA LinkGeneric 02/2017
1	AntacidsIBA 02/2017
1	lafutidineIBA 02/2017
1	Histamine H2 AntagonistsIBA 02/2017
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2017
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2017
1	mirdametinibIBA 01/2017
1	BucladesineIBA 01/2017
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2017
1	Protein Kinases (Protein Kinase)IBA 01/2017

Therapy/Procedure

23	Gastrectomy 10/2020 - 01/2000
14	Lymph Node Excision (Lymph Node Dissection) 01/2013 - 01/2000
10	Lasers (Laser) 02/2022 - 01/2005
6	Drug Therapy (Chemotherapy) 02/2017 - 01/2000
5	Hepatectomy 05/2013 - 01/2000
4	Therapeutics 08/2001 - 10/2000
3	Pancreaticoduodenectomy 01/2018 - 01/2000
2	Renal Dialysis (Hemodialysis) 01/2019 - 02/2005
2	Adjuvant Chemotherapy 06/2011 - 11/2000
2	Combination Drug Therapy (Combination Chemotherapy) 12/2001 - 07/2001
2	Radiotherapy 12/2001 - 05/2001
2	Chemoprevention 10/2001 - 08/2001